Description

What is Selank?

Selank is a synthetic heptapeptide derivative of the human peptide Tuftsin, developed for its anxiolytic and nootropic properties. It acts as a stable regulatory peptide that modulates the expression of Brain-Derived Neurotrophic Factor (BDNF) and balances the degradation of enkephalins. Clinically used in Russia for Generalized Anxiety Disorder (GAD), it offers a unique non-sedating effect, improving mood, focus, and cognitive function while reducing stress and anxiety.

Physiological Benefits

✔Potent Anxiolytic Effects: Reduces anxiety, worry, and restlessness without sedation or cognitive dulling, making it highly functional for daily use.
✔Stress Resilience and Adaptation: Helps the body and mind adapt to and recover from acute and chronic stressors, both psychological and physiological.
✔Cognitive Enhancement (Nootropic): Improves memory formation, learning capacity, and mental clarity, particularly under conditions of stress or fatigue. This is strongly linked to its BDNF-elevating mechanism.
✔Mood Stabilization and Anti-Anhedonia: Can elevate mood and restore the ability to feel pleasure in individuals suffering from stress-induced anhedonia or mild depression.
✔Neuroprotective Properties: Protects neurons from damage caused by hypoxia, excitotoxicity, and other insults, suggesting potential applications in recovery from brain injuries.
✔Favorable Safety Profile: Lacks the significant side effects of traditional anxiolytics, such as physical dependence, withdrawal syndrome, amnesia, and motor impairment.
✔Immunomodulatory Action: Balances the immune system, particularly under stress, and has demonstrated antiviral properties (against influenza virus in vitro/vivo) by modulating interferon production.
✔Reduction of Asthenia: Combats mental and physical fatigue, particularly that associated with chronic anxiety or post-illness recovery.
✔Accelerated Recovery from Neurological Insults: Preclinical models show it may aid in recovery from conditions like stroke or nerve damage by reducing neuroinflammation and promoting neurogenesis.
✔Synergy with other Therapies: Can be used alongside other treatments for anxiety and depression to potentially enhance their efficacy or reduce their side effects.

Use Cases

Generalized Anxiety Disorder (GAD)

Its primary approved indication. Used to manage chronic worry, tension, and fear.

Adjustment Disorder

Helps individuals cope with significant life stressors (e.g., job loss, bereavement).

High-Stress Professions

Utilized by professionals (e.g., executives, first responders) to maintain cognitive performance and emotional stability under pressure.

Academic and Exam Preparation

Students use it to enhance learning, improve memory consolidation, and reduce exam-related anxiety.

Post-Viral Cognitive Dysfunction

Investigational use for clearing “brain fog,” improving focus, and reducing fatigue following viral illnesses.

Phobia and Panic Attack Management

As an adjunct, it can help reduce the baseline anxiety that contributes to phobic responses and panic.

Withdrawal from Benzodiazepines or Alcohol

Its non-addictive nature and GABAergic modulation may help mitigate withdrawal symptoms and cravings (preclinical evidence).

Immune Support during Stressful Periods

Taken prophylactically during periods of high stress (e.g., travel, intense work projects) to prevent stress-induced illness.

Enhancing Psychotherapy

By reducing anxiety, it can make patients more receptive to cognitive-behavioral therapy (CBT) and other therapeutic modalities.

Mild Traumatic Brain Injury (TBI) Recovery

Experimental use to reduce neuroinflammation and promote neural repair via BDNF upregulation following concussion.

Focus and Productivity Enhancement

Used by individuals in the biohacking community to achieve a calm, focused mental state conducive to deep work.

Common Research Protocols

⚠ Research Use Only

The following data is for educational purposes only. Lanna Peptides compounds are not for human consumption.

Route	Typical Dosage Range	Frequency	Notes
Subcutaneous (Injection)	200 – 500 mcg per day	Once daily.	Administered daily. Provides stable systemic absorption and precise dosing control. Effective for sustained immunomodulatory and anxiolytic support.

Need more technical data?

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