Description
What is CJC-1295?
CJC-1295 is a synthetic analogue of Growth Hormone-Releasing Hormone (GHRH) designed to stimulate the pituitary gland to release endogenous growth hormone (GH). By mimicking the body’s natural signaling, it promotes increases in plasma GH and Insulin-Like Growth Factor 1 (IGF-1) levels without the side effects associated with exogenous HGH administration. Key benefits include increased lean muscle mass, fat loss, improved sleep quality, and accelerated injury recovery. It is most frequently used in combination with a Growth Hormone Releasing Peptide (GHRP) like Ipamorelin to effectively amplify natural growth hormone production.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide and a highly selective agonist of the ghrelin receptor (GHS-R1a), functioning as a growth hormone secretagogue. Distinct from other GHRPs, it stimulates a strong, pulsatile release of growth hormone without causing significant spikes in cortisol, prolactin, or appetite. This “clean” side effect profile makes it a preferred choice for anti-aging, body composition improvement, and injury recovery. It is frequently stacked with GHRH analogues to synergistically amplify natural growth hormone production.
Physiological Benefits
- ✔Increased Lean Body Mass: GH and IGF-1 are highly anabolic, promoting muscle protein synthesis and hyperplasia (increase in muscle cell number). (Ibebunjo et al., 2013)
- ✔Reduced Adipose Tissue (Fat Loss): GH stimulates lipolysis, the breakdown of triglycerides in fat cells, and promotes the use of fat for energy.
- ✔Improved Sleep Quality: GH release is intrinsically linked to deep sleep (slow-wave sleep). Users frequently report deeper, more restorative sleep and vivid dreams.
- ✔Enhanced Skin Health and Elasticity: IGF-1 promotes collagen synthesis, leading to improved skin thickness, reduced wrinkles, and a more youthful appearance.
- ✔Accelerated Injury Recovery: By promoting cellular proliferation and collagen synthesis, elevated GH/IGF-1 can speed the healing of tendons, ligaments, and muscle tissue.
- ✔Increased Bone Mineral Density: GH and IGF-1 play a crucial role in bone remodeling and mineralization, potentially helping to prevent or reverse osteopenia over the long term.
- ✔Improved Immune Function: GH can support the proliferation and function of immune cells, though this is a complex and multifaceted effect.
- ✔Enhanced Cognitive Function: Some users report improved focus, memory, and mental clarity, potentially linked to better sleep quality and the neurotrophic effects of IGF-1.
- ✔Cardioprotective Effects: Studies on GHRH analogs have suggested potential benefits for cardiovascular health, including improved cardiac output in certain patient populations.
- ✔Amplified Effects with GHRPs: When combined with a GHRP like Ipamorelin, all the above benefits are significantly amplified due to the synergistic and larger release of GH.
Use Cases
To increase muscle mass, reduce body fat, and improve recovery between training sessions. (Most common use case).
To restore youthful GH/IGF-1 levels, improving skin, energy, sleep, and overall vitality.
To accelerate the healing of tendonitis, ligament sprains, and muscle tears, often in combination with peptides like BPC-157 or TB-500.
To minimize muscle catabolism and speed up tissue healing after medical procedures.
Specifically used to enhance the depth and restorative quality of sleep. Mod GRF (1-29) + Ipamorelin before bed is a very common protocol.
The original intended use case, to restore normal GH levels in adults with pituitary insufficiency.
The anabolic properties make it a candidate for reversing muscle loss associated with chronic illness or aging.
The focus of ConjuChem’s Phase II trials, aimed at reducing visceral adipose tissue accumulation.
For individuals with osteopenia or at risk of osteoporosis, as part of a broader therapeutic strategy.
For individuals seeking to optimize metabolic health, energy levels, and overall physical function.
Common Research Protocols
⚠ Research Use Only
The following data is for educational purposes only. Lanna Peptides compounds are not for human consumption.
General Dosing Guidelines
Start low to assess individual tolerance.
- Beginner: 200mcg Blend (100mcg each peptide), once daily before bed.
- Standard: 400mcg Blend (200mcg each peptide), once daily before bed.
- Advanced / Athletes: 600mcg Blend (300mcg each peptide).
- Option: Split into AM/PM doses (e.g., 300mcg Blend each time).
- Weight Adjustment:
- < 150lbs: 200-300mcg Blend daily.
- 150-200lbs: 400mcg Blend daily.
- 200+lbs: 500-600mcg Blend daily.
Optimal Timing
- Empty Stomach: Administer 30-60 minutes before meals OR 2-3 hours after meals.
- GLP-1 Users: Increase wait time to 3-4 hours after meals.
Common Cycling Protocols
- Weekly: 5 days on / 2 days off (prevents desensitization).
- Cycle Length:
- 8-16 weeks on, followed by 4-6 weeks off.
- Alternatively: 3 months on, 1 month off.
| Route | Focus Area | Typical Dosage | Frequency | Notes |
|---|---|---|---|---|
| Subcutaneous | Muscle Growth & Strength | 400-600mcg Blend (200-300mcg each) |
1-2 times daily | Protocol: Administer post-workout (AM) and pre-bed (PM). Cycle: 12-16 weeks on, 4-6 weeks off. Note: Boosts GH/IGF-1 for protein synthesis. |
| Subcutaneous | Recovery & Injury Healing | 200-600mcg Blend (100-300mcg each) |
1-2 times daily | Protocol: Post-workout and pre-bed. Cycle: 8-16 weeks. Note: Can be stacked with BPC-157 or TB-500. |
| Subcutaneous | Anti-Aging & Vitality | 200-400mcg Blend (100-200mcg each) |
Once daily | Protocol: Administer before bed. Cycle: 3 months on / 1 month off. Note: Focuses on skin health, energy, and cognitive/mood boosts. |
| Subcutaneous | Fat Loss & Body Composition | 200-400mcg Blend (100-200mcg each) |
Once daily | Protocol: Administer before bed. Cycle: 8-12 weeks. Note: Best combined with fasting (16-18h) & cardio. |
| Subcutaneous | Sleep Quality & Wellness | 200-400mcg Blend (100-200mcg each) |
Once daily | Protocol: Strictly before bed. Cycle: 8-12 weeks. Note: Enhances slow-wave sleep and dream recall. |
Need more technical data?
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